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Tag: News

Amid COVID-19, Pro-Lifers Push to Avoid Abortive Fetal Cel…… | News & Reporting

Philip Shober

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Ionis’ inhaled antisense medicine demonstrates potential as a novel treatment for cystic fibrosis | News

CARLSBAD, Calif., Oct. 13, 2020 /PRNewswire/ — Ionis Pharmaceuticals, Inc. (NASDAQ: IONS), the leader in antisense therapeutics, announced today that data from a clinical trial of IONIS-ENAC-2.5Rx demonstrated a significant decrease in the expression of epithelial sodium channel (ENaC) in subjects with cystic fibrosis (CF). The study showed a mean 55.6 percent decrease (p<0.05) in ENaC mRNA expression at the 75 mg dose in the multidose segment of the trial. The study represents the first time an antisense medicine delivered directly to the lung via a nebulizer has shown a significant reduction in ENaC messenger RNA levels. In preclinical studies, ENaC mRNA reductions of 40 percent or more resulted in significant improvement in mouse models of CF lung disease.

IONIS-ENAC-2.5Rx is an investigational antisense medicine designed to reduce the expression of ENaC in the lung. ENaC is believed to be hyperactive in cystic fibrosis, which is caused

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Takeda Group Begins Manufacturing COVID-19 Plasma Treatment Ahead of Approval | Top News

NEW YORK (Reuters) – The Takeda Pharmaceutical Co-led group that is developing a blood plasma treatment for COVID-19 has started manufacturing while the late-stage trial to determine whether it works is ongoing, Takeda Chief Executive Christophe Weber said on Monday.

The group, known as the CoVIg Plasma Alliance, enrolled its first patient in the Phase III trial on Friday after months of delays. It aims to enroll 500 adult patients from the United States, Mexico and 16 other countries and hope to have results by the end of the year.

“The likelihood it works is very high,” Weber said in an interview. “And that’s why we have launched a campaign in order to accelerate the donation of convalescent plasma to manufacture and produce this product.”

The alliance, which includes CSL Behring, Germany’s Biotest AG and other companies, is testing a hyperimmune globulin therapy, which is derived from blood plasma of

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MYXfitness Is The First At-Home Fitness Brand to Integrate National News, Plus a Full Suite of Revolutionary Content On Its Platform

MYX’s member research shows content variety outside of structured workouts is becoming an important factor in what people crave as they tackle fitness at home. While on-demand, one-on-one coaching is essential, catching up on the news, virtually exploring an exotic locale or discovering motivational content, might be what the day calls for. MYX Media provides members those options and more, while still integrating heart-rate data as a powerful measure and motivator.

“Adding MYX Media to our one-on-one coaching and customized heart-rate training, further positions MYX as the most personalized experience in at-home fitness,” says Heberto Calves, President of MYXfitness. “The fitness-tech industry at large seems disproportionately focused on the competitive, ‘workout to win’ consumer. The MYX content and experience speak to the 58% of the market that identifies as ‘workout for life’. These

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Study Probes Links in Asthma, Food Sensitivity and Irritable Bowel Syndrome | Health News

By Robert Preidt, HealthDay Reporter

(HealthDay)

MONDAY, Oct. 12, 2020 (HealthDay News) — Teens who had asthma and food hypersensitivity when they were younger are at increased risk of irritable bowel syndrome (IBS), researchers report.

For the study, the investigators examined the health of 2,770 children from birth to age 16. Kids with IBS at age 16 were more likely to have had asthma at age 12 (about 11% versus 7%).

In addition, the researchers found that 16-year-olds with IBS were more likely to have had food hypersensitivity at age 12 (41% versus 29%).

Asthma, food hypersensitivity and eczema (a condition that makes your skin red and itchy) were all associated with an increased risk of concurrent IBS at age 16, the findings showed.

“The associations found in this large study suggest there’s a shared pathophysiology between common allergy-related diseases and adolescent irritable bowel syndrome,” said study leader Jessica Sjölund,

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Abbott Wins U.S. Emergency Use Authorization for New COVID-19 Antibody Test | Top News

(Reuters) – Abbott Laboratories said on Monday the U.S. Food and Drug Administration has issued an emergency use authorization for its lab-based COVID-19 antibody blood test.

The test, AdviseDx, can be used to identify a type of antibody called Immunoglobulin M (IgM) in blood samples to determine if someone has been exposure to the novel coronavirus, potentially indicating a recent or prior infection.

Abbott has already received emergency use authorization for seven tests, including molecular tests, a rapid antigen test and another test which can detect a type of antibody called IgG.

The FDA’s emergency use authorization allows the use of unapproved medical products in an emergency to diagnose, treat, or prevent serious or life-threatening diseases with no adequate or approved alternatives.

IgG is longer lasting in the body after an infection, but IgM is more useful for determining a recent exposure to the coronavirus as these antibodies become undetectable

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As Globe Gallops Into Vaccine Trials, Insurers Remain Unfazed | Top News

By Noor Zainab Hussain, Carolyn Cohn and Ludwig Burger

LONDON/FRANKFURT (Reuters) – The world is racing towards a vaccine in record time, stirring public concerns about safety to the extent that nine leading developers have felt compelled to issue a pledge to uphold scientific standards and testing rigour.

Yet, while more than 40 experimental COVID-19 vaccines are being tested on humans, the insurance companies with decades of experience in assessing the risks of clinical trials don’t see anything to be unduly concerned about.

Executives at insurer Allianz and brokers Gallagher and Marsh, among the leading players in clinical trials insurance, told Reuters that premiums had only marginally increased so far in the current pandemic.

They argued there was little structural difference to trials carried out in the past, despite drugmakers around the world competing to shatter the fastest time in history for developing a vaccine, which stands at around four

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Czechs to Tighten Coronavirus Measures as Infections Soar: PM | World News

PRAGUE (Reuters) – The Czech government will tighten coronavirus measures from Wednesday to curb soaring infections and hospitalisations but will seek to avoid the kind of blanket lockdown imposed in the spring, government officials said on Sunday.

The nation of 10.7 million has recorded Europe’s fastest rate of growth in new cases per capita in recent weeks after authorities eased most restrictions during the summer following a tough lockdown at the start of the pandemic.

“We have to decide on further measures, that will happen on Monday at the government session, and the measures will be effective from Wednesday,” Prime Minister Andrej Babis said in a video message on YouTube.

He did not give any details on the measures.

Finance Minister Alena Schillerova said earlier on Sunday that the government sought to avoid the complete lockdown the country experienced in spring.

“We don’t want to switch off the economy. We

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Soaring Virus Infection Puts More French Cities on Alert | World News

PARIS (AP) — Four French cities have joined Paris and Marseille in the maximum alert status to fight the spread of the coronavirus, and it appeared likely that the list would soon grow as infections soar.

Bars shut down and other severe measures are ordered under maximum alert.

Lyon, Grenoble and Saint-Etienne in the southeast and Lille in the north moved to maximum alert on Saturday when health authorities reported nearly 26,900 new daily infections in 24 hours. There were just under 5,000 new hospitalizations over the past week, with 928 of them in ICUs, and the positive rate for the increasing number of COVID-19 tests climbed to 11%. Nearly 32,690 coronavirus deaths have been counted in France, but the actual number is likely higher due to deaths at home and incomplete reporting from hospitals or rest homes.

While France girded itself for a climb in critical numbers, a consultation

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Trump Insists He’s Free of Virus, Ready for Campaign Trail | Political News

By JONATHAN LEMIRE, Associated Press

President Donald Trump on Sunday declared he was healthy enough to return to the campaign trail, a day after the White House doctor said he was no longer at risk of transmitting the coronavirus but did not say explicitly whether Trump had tested negative for it.

Trump, who was poised Monday to host his first rally after his COVID-19 diagnosis, declared he was now “immune” from the virus, a claim that was impossible to prove and comes amid a series of outstanding questions about the president’s health.

“I’m immune,” Trump said in an interview on Fox News. “The president is in very good shape to fight the battles.”

In a memo released Saturday night by the White House, Navy Cmdr. Dr. Sean Conley said Trump met the Centers for Disease Control and Prevention criteria for safely discontinuing isolation and that by “currently recognized standards” he

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